Aplastic Anemia & Myelodysplasia Association of Canada (AAMAC)
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We are currently working on a process to call for research proposals, evaluate them and award them. Additional information will be posted here as it becomes available.

AAMAC funds research into bone marrow failure diseases such as aplastic anemia, PNH and MDS. The following are current examples of work we at AAMAC are proud to fund.

Pediatric Research through the C17 Research Network

The C17 Research Network is a Canada-wide group of pediatric hematology and oncology researchers working in the 17 pediatric cancer centres across the country. These researchers also work with the Children's Oncology Group (COG), an international research group of more than 240 hospitals that conduct clinical trials for children with cancer.

AAMAC is currently co-funding a study being conducted by Dr. Dror and his team at SickKidsâ in Toronto. The title is the “Canadian Aplastic Anemia and Myelodysplastic Syndrome Study”. The project includes the opening of a registry and initiating the first study to apply next generation sequencing to identify genetic predispositions that affect treatment decisions in aplastic anemia.

The grant is for $22,500/year for two years and is matched by the C17 Research Network and the first payment was awarded in the fall of 2014. This amount is sufficient for the setup of the registry but additional funding is needed to start the identification of genetic predispositions affecting treatment choices. AAMAC considers this a vital part of the research project and awarded Dr. Dror and his team an additional $25,000 in late 2015 in the hope he will be able to obtain the additional funding required for this part of the project.

Both a registry and knowing what treatment will work best for a patient will be a big step forward in their treatment.

Iron overload in RARS versus non-RARS MDS

In February, 2016, AAMAC awarded Dr. Heather Leitch, Providence Haematology, Vancouver, almost $20,000 to continue her research into iron overload in MDS-RARS versus non-RARS-MDS. Observations suggest that RARS cells may be relatively protected against iron induced damage, and may process iron differently than non-RARS MDS.

In conjunction with the Canadian Institute for Health Research (CIHR)

In the past AAMAC has worked with the now discontinued CIHR Small Health Organizations Partnership Program (SHOPP) to find projects relevant to AA, PNH or MDS or the more general bone marrow failure diseases. This was a great benefit to AAMAC because CIHR would evaluate and rate proposals for scientific expertise and relevance and forward them to us for consideration.

We currently have one on-going research project in conjunction with CIHR SHOPP. The project is the “Role of Innate Immune Signaling in Myelodysplastic Syndromes” and is being done by Dr. Linda Chang under the supervision of Dr. Aly Kharsan at the BC Cancer Agency, Genome Sciences Centre. The grant is for $60,000 over several years and is matched by CIHR.

Annual Canadian Nurses Foundation Grant

AAMAC has supported a Canadian Nurses Foundation grant since 2000. The grant is awarded by the Foundation to individuals pursuing graduate nursing studies who specialize in oncology/hematology or who have oncology/haematology as the focus of their research. The Foundation is a national non-profit charitable organization founded in 1962 by the Canadian Nurses Association.

The 2015-2016 AAMAC Grant winner is Philiz Goh of the University of Toronto. Philiz cares for oncology patients throughout their cancer journey and plans to mentor and support nurses to provide quality care for all oncology patients. Philiz continues her leadership role at both the regional and national level with the Canadian Association of Nurses in Oncology (CANO), while both publishing and presenting her research findings at national and international conferences.

For a recipient list of nursing scholarships please click here.

Past research initiatives click here.

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